According to the World Health Organization (WHO), “the post-antibiotic era”, where no treatment for infections and minor injuries exists, is near. The decreasing effectiveness of antibiotics and other antimicrobial agents is a global concern. The synthesized and deposited nanoparticles exhibited an inhibitory effect upon S. The use of the argon atmosphere contributed to reduce significantly the formation of Cu oxide species. The obtained deposits consisted of porous coatings composed of copper and copper oxide nanoparticles interconnected to form chain-like aggregates. The UV-VIS absorbance of the thin layer of nanoparticles was also measured, and the antibacterial capacity of the obtained deposits tested against Staphylococcus aureus. Size, morphology, composition and the crystalline structure of the produced nanoparticles have been studied by the means of field emission scanning electron microscopy (FESEM), high resolution transmission electron microscopy (HRTEM), the energy dispersive spectroscopy of X-rays (EDS), selected area electron diffraction (SAED) and X-ray diffraction (XRD). In this work, Cu and Cu oxide nanoparticles were synthesized by laser ablation in open air and in argon atmosphere using 5 nm radiation generated by nanosecond and picosecond Nd:YVO 4 lasers, respectively, to be directly deposited onto Ti substrates. Copper nanoparticles and their huge potential as a bactericidal agent could be a solution. Laboratory of Applied Organic Synthesis, Faculty of Exact and Applied Sciences, University Oran1 Ahmed Ben Bella, PO Box 1524, El M’Naouer, 31000, Oran, Algeriaĭepartment of Electronics, Faculty of Technology, University of Saïda Dr.The proximity of the “post-antibiotic era”, where infections and minor injuries could be a cause of death, there are urges to seek an alternative for the cure of infectious diseases. Laboratory of Materials and Catalysis, Faculty of Sciences, Site I BP 89 Djillali Liabès’s University, 22000, Sidi Bel-Abbès, Algeria Laboratory of Separation and Purification Technology, Department of Chemistry, Faculty of Science, University of Tlemcen, Tlemcen, Algeria Institute of Functional Interfaces Section, Karlsruhe Institute of Technology (KIT), 76344, Eggenstein-Leopoldshafen, Karlsruhe, Germanyīiotoxicology Pharmacognosy and Biological Valorization of Plants Laboratory, Department of Biology, Faculty of Science, University of Saïda Dr. Moulay Tahar, Saida, 20000, Saida, Algeria Moulay Tahar, Saida, 20000, Saida, Algeriaĭepartement of Engineering Process, Faculty of Technology, University Dr. Laboratory of Physico-Chemical Studies, University Dr. Rodrıguez-Fuentes, Microporous Mesoporous Mater. MezaFuentes, Revista Colombiana de Química 45, 33–38 (2016) The obtained results of the application of Cu-LDHs antibacterial inhibitors seem to be quite promising material in the antibacterial fields. The Cu 0.10–Al 0.10-LDHs sample shows high activity against all types of bacteria either for calcined or uncalcined materials. The antibacterial activity of Cu-LDHs with various molar ratios Cu/Al and their calcined phases were estimated towards multiple types of bacteria ( Escherichia coli, Pseudomonas aeruginosa, Enterococcus faecalis, Staphylococcus aureus, and Bacillus Subtilis). The particular surface areas are ranging between 40 and 92 m 2/g, while the calcined samples showed the formation of Cu and Mg oxides. The best structure is attributed to the sample Cu 0.05–Al 0.15-LDHs. The uncalcined solids showed clear hydrotalcite-like crystalline phases having a particle measurement between 5 and 16 nm. The uncalcined and calcined Cu-LDHs were characterized by powder X-ray diffraction and N 2 adsorption–desorption. A range of Cu-LDHs has been synthesized by co-precipitation using metal nitrate precursors and sodium carbonate under varying molar ratios Cu/Al (Cu 0.05–Al 0.15, Cu 0.10–Al 0.10, Cu 0.14–Al 0.06, and Cu 0.15–Al 0.05).
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